By Rodolfo Paoletti, Dr. David Kritchevsky
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Distributions 47 PRELIMINARY RELATIONSHIPS OBSERVED BETWEEN Sf RATE AND LIPOPRO TEIN CONCENTRATIONS One of the capabilities of the present methodology is the evaluation of potential relationships that may exist between flotation rate of the major component of the Sf 0-12 lipoprotein class and the concentration of each narrow segment of both the high- and low-density lipoprotein spectra. Such a relationship might indicate, for instance, that a certain lipoprotein profile is associated with either a slow or fast Sf° rate of the major 0-12 class.
C. PRELIMINARY RELATIONSHIPS OBSERVED BETWEEN LIPOPROTEIN CON CENTRATION, LIPOPROTEIN COMPOSITION, AND OTHER PARAMETERS The lipid classes making up substantially all of the serum (or lipopro tein) lipids are cholesteryl esters, triglycerides, phospholipids, and unesterified cholesterol, the first three of these comprising about 90% of the total. The amount of unesterified fatty acids is negligibly small except in the high-density fraction, where it occurs to the extent of a few per cent. Triglycerides, as measured, may contain small amounts of diglyc4 Mills and Wilkinson (21) observed higher Sf° rates than we have, although the methods of calculating the Sf ° rate and the F versus C dependence (including the K value) were different.
1. 2. 3. Variable no. 4 Std. dev. Std. 0 Mean Std. error Variable Std. dev. Males Table II MEAN VALUES FOR SERUM LIPIDS AND LIPOPROTEINS AND LIPID COMPOSITION OF PRINCIPAL LIPOPROTEIN FRACTIONS 50 EWING ET AL. I. I. 175(S f ° 12-400) 24. 22. 23. 21. 20. 18. 19. 17. 16. 15. 14. I. units) ( w t % of total lipids) ( w t % of total lipids) (mg/100 ml) (Svedberg units) (mg/100 ml) ( m g / 1 0 0 ml) ( w t % of total lipids) Human Serum Lipoprotein Distributions 51 52 E W I N G E T AL. sum of individual components (including calculated values of unesterified cholesterol) is usually a good approximation of the total extracted weight.